American artist Andrew Wyeth died on Friday in his Philadelphia home, according to a spokeswoman for the Brandywine River Museum near his home in Chadds Ford, Pennsylvania.

Wyeth, 91, has well-known for his paintings of people and landscapes of Pennsylvania's Brandywine Valley and coastal Maine.

One of his most famous ones is Christina's World, painted in 1948, which shows his Maine neighbor stretched out in a field looking at a house. It is currently at the Museum of Modern Art in New York.

Museum spokeswoman Hillary Holland said Wyeth died on Friday morning. She said Wyeth died in his sleep at his house in Chadds Ford with his family by his side.

Wyeth was given a National Medal of the Arts by President Bush in 2007 in recognition of a lifetime of paintings whose meticulous realism have captured the American consciousness, and whose austere vision has displayed the depth and dignity of American life.

His artworks also commanded some of the highest prices of any living U.S. artist. A tempera painting of a horse sold for $4.4 million at a Sotheby's auction in 2006, according to AskART, an online database.

Pennsylvania