Barack Obama's administration has done little to dispel questions about what might be holding up full implementation of the prisoner agreement.
The release of all 53 is not a pre-condition for holding talks on migration and on the eventual normalization of relations.
Some members of Congress have predicted tough battles over implementing President Obama’s historic Cuba policy shift.
The largest demonstration was scheduled to take place in front of the White House at 10 a.m.
Some experts believe North Korea's alleged involvement in the hacking of Sony might put the country back on the list.
Fun things to know about Joseph Gordon-Levitt's wife Tasha McCauley.
The three other Cubans, all in their 20s and 30s, made it to shore clinging to two inner tubes.
The president will travel to three different states this week to preview the jobs, housing and higher-education portions of his State of the Union address.
Sen. Marco Rubio addressed speculation about his potential candidacy in a Wednesday interview.
Police arrested several political opponents on Tuesday and kept others under virtual house arrest ahead of a protest.
The United States on Wednesday condemned what it called Cuba's practice of repression following the detention of several activists.
The Obama-led administration has so far released nearly 30 prisoners from the facility in 2014, reducing the number of detainees to 127.
“Today’s detentions in Havana are a reminder that change won’t happen overnight in Cuba," the head of #CubaNow said.
Dissident leaders say they were not consulted when the list of prisoners to be freed was drawn up.
Jeb Bush has released some of his emails as he prepares for a possible U.S. presidential bid in 2016.
Most of the remaining Gitmo prisoners are either too dangerous or Yemeni, or both. And Yemen is one of al Qaeda’s global strongholds.
Pope Francis will celebrate his second Midnight Mass as pontiff on Wednesday evening.
U.S. Sen. Rand Paul, R-Ky., tweeted that he thinks a "Rand Paul 2016" mock turtleneck "will be a popular item this year."
Clifford Sloan will step down as the U.S. State Department's envoy to Guantanamo Bay.
Gen. Mark Milley will decide if any action should be taken against former Taliban captive Sgt. Bowe Bergdahl.
The North accused the U.S. of involvement in making "The Interview," which revolves around a plot to kill Kim Jong Un.
In a televised speech, Raul Castro pledged that renewal of U.S. relations would not end communism in Cuba.