Dallas Cowboy vs. New York Giants 2018: Prediction, Betting Odds, Injury News, Preview For Week 17 Matchup

The NFC East champion Dallas Cowboys (9-6) enter the final week of the season with an eye on their wild-card opponent, while the New York Giants (5-10) are looking to end 2018 on a high note, when the division rivals meet Sunday at MetLife Stadium in East Rutherford, New Jersey.

The Cowboys locked up the No. 4 seed and will host a wild-card team at AT&T Stadium on either Jan. 5 or Jan. 6. The most likely opponent is the Seattle Seahawks, who need a win over the Arizona Cardinals to ensure a date with the Cowboys. Dallas could face the Minnesota Vikings if the Seahawks lose and the Vikings beat the Chicago Bears. The Cowboys will not face the Philadelphia Eagles, who are still in the playoff hunt.

"I certainly think we're playing the kind of really good football that you can win games in postseason," owner and general manager Jerry Jones said, according to ESPN. "Any of the teams can win the game. We right here had the Giants come right up the backside and win the championship [in 2007]. I think our team is a postseason team."

In Monday's injury report, the Cowboys listed defensive tackle David Irving, linebacker Sean Lee, cornerback Anthony Brown and wide receiver Tavon Austin as "out," while defensive end Tyrone Crawford was listed as "questionable."

The Giants also have several players out. Wide receiver Odell Beckham Jr., center Spencer Pulley, linebacker Alec Ogletree, wide receiver Russell Shepard and defensive end Kerry Wynn are all sidelined.

The Giants have the 19th-best offense (350.4 yards per game), while the Cowboys have the 23rd-best offense (338.8). The Cowboys have the sixth-best defense (321.8), while the Giants have the 22nd-best defense (368.2).

With the playoffs looming, Cowboys head coach Jason Garrett is expected to use more of his bench against the Giants.

When the two teams met in Week 2, the Cowboys' defense sacked Eli Manning six times in a 20-13 home win.

Betting Line: Giants -6 points

Over/Under: 41.5

Prediction: The Giants will be playing in front of their home crowd, while the Cowboys will be looking to enter the playoffs with a healthy roster. Expect the Giants to run some clever plays and come away with a win.

Giants over Cowboys, 21-10