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LeGarrette Blount celebrates his touchdown with Carson Wentz in the fourth quarter against the San Francisco 49ers. Getty

The Denver Broncos will look to snap a three-game losing streak when they head to Philadelphia to face the surging Eagles on Sunday at Financial Financial Field.

There are interesting storylines for both offenses as they face two impressive defenses. Denver turns to Brock Osweiler, who replaces starting quarterback Trevor Siemian, while the Eagles' offense will be without star offensive tackle Jason Peters against a formidable Broncos pass rush.

Running back Jay Ajayi makes his debut with the Eagles after being acquired Tuesday from the Miami Dolphins. The Pro Bowl rusher has averaged just 3.4 yards per carry through seven games with two subpar performances against the New York Jets' strong rush defense. Without Peters, Ajay and LeGarrette Blount will be facing the No. 1 rush defense in the league. Denver hasn't allowed a rushing touchdown all season.

The Broncos' offense has sputtered and is coming off a difficult road loss to the Kansas City Chiefs. Denver will try their reverse their fortunes with Osweiler after Siemian threw three disappointing interceptions. Osweiler has thrown just four passes this season after struggling as the Houston Texans starting quarterback in 2016. The running game has scored just four touchdowns this season and will face the No. 2 rush defense in the league.

The Eagles look to Carson Wentz to continue his impressive play. The second-year quarterback leads the NFL with 19 touchdowns and 2,603 yards. But the 24-year-old has also thrown an interception in consecutive games and will be facing a defense that boasts star cornerbacks Chris Harris Jr. and Aqib Talib.

“There’s high tension, man,” Harris said after the Broncos’ 29-19 defeat to the Chiefs on Monday. “We’re not winning. We’re not taking care of the football. We’re giving the games away.”

The opening spread had the Eagles favored by seven points. According to betting site Bovada, the Eagles now have an eight-point advantage.

The Broncos have a 2-4-1 record vs. the spread, while the Eagles have a 6-2 record vs. the spread.

Line: Eagles -8

Over/Under: 42 points

Predicted Score: Eagles over Broncos, 17-14