The Northern Plains, Upper Midwest, Northeast and New England areas are under a major wind chill alert Monday that is forecasted to bring dangerously cold air.

The wind chills will get as low as 45 below zero for the Upper Midwest and 35 below zero for the Northeast and New England.

“Behind a potent cold front that has exited into the eastern Atlantic Ocean, arctic air is expected to continue rushing into the Northeast this morning. This pocket of cold air extends westward and throughout much of the northern tier, where dangerously cold wind chills will remain across the Upper Midwest and Great Lakes today before more bearable temperatures enter on Tuesday,” National Weather Service said.

The cold front stretches 250 miles from Lake Ontario to Massachusetts and could affect 15 million people.

The coldest day of the week for the Upper Midwest and Great Lakes will be on Monday, with the worst of it to last until Tuesday morning.

The cold front on Tuesday is expected to bring the coldest “high temperature forecast” in three years for New York at 22 degrees and Boston at 12 degrees.

The National Weather Service warns “temperatures this cold can lead to frostbite on exposed skin in as little as 10 minutes.”

Around 5 million people were under a weather alert Monday morning in the Great Lakes. The extremely low wind chills are expected to bring snow to place around Cleveland and Buffalo and Syracuse, New York. Some parts are expected to possibly see two feet of snow.