Holiday travel could be disrupted across the U.S. as two major storm systems bring snow, rain and wind to separate parts of the country. The day before Thanksgiving is historically one of the busiest travel days of the year.

The first system, known as a "bomb cyclone", hit Western states overnight with heavy rain in low-lying areas, and heavy snow in more mountainous regions. The system also features powerful winds of up to 100 mph.

The system has already caused blizzard conditions on Tuesday night in southwestern Oregon and Northern California.

The other storm system hits Northern New England with rain in addition to gusty winds on Thanksgiving, likely disrupting travel at airports in the region. The high-speed 40 mph winds could be problematic for high-flying balloons during Macy's Thanksgiving Day Parade in New York City.

On Wednesday, winds of up to 50 to 60 mph hit major Midwestern cities such as Chicago. The Minneapolis-St.Paul area also saw its first major snowstorm overnight, leaving 6-10 inches of snowfall in some areas.

Colorado has also seen snowfall of up to three feet in some areas, with almost 500 flights canceled Tuesday at Denver International Airport.

The American Automobile Association (AAA) has said that 55 million Americans will drive, take a train, or fly Wednesday. This week will be the busiest week of the year for passenger railroad service Amtrak. Atlanta's Hartsfield-Jackson airport anticipates around 1.3 million air passengers between Wednesday and Sunday.