Hollywood may have some Charlie Sheen-types who turn on a whim against their friends and their employers, but many stars have managed to stay grounded with the love and support of their Tinseltown buddies. Here is a look at some of showbiz's biggest friendships.

George Lopez
Cast member George Lopez gestures at the premiere of "Valentine's Day" at the Grauman's Chinese theatre in Hollywood, California February 8, 2010. REUTERS
Leonardo di Caprio
Leonardo di Caprio Reuters
Tim Burton with actor Johnny Depp
Johnny Depp (L) and director Tim Burton stand on stage during a panel discussion on the movie 'Alice in Wonderland' during the 40th annual Comic Con Convention in San Diego July 23, 2009. Reuters Photo
Anne Hathaway
Anne Hathaway Reuters
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