NFL 2018 Week 10 Lines: Point Spreads, Betting Odds From Las Vegas, Online Sportsbooks

Patrick Mahomes Philip Rivers Chiefs Chargers — Patrick Mahomes #15 of the Kansas City Chiefs and Philip Rivers #17 of the Los Angeles Chargers shake hands at the end of the game after a 38-28 Chiefs win at StubHub Center on September 9, 2018 in Carson, California. Harry How/Getty Images

Big NFL favorites have been covering with consistency in the 2018 season, and there are plenty of large betting lines on the upcoming schedule. Three Week 10 contests feature double-digit point spreads, and five teams are laying more than a touchdown.

The Kansas City Chiefs are the second-biggest favorites of the season. The Arizona Cardinals are 16.5-point underdogs in their visit to Arrowhead Stadium, and they hope to make history like the Buffalo Bills did in Week 3. Buffalo beat the Minnesota Vikings on the road 27-6 as 17-point underdogs.

The Los Angeles Rams are 10-point favorites against the Seattle Seahawks in a contest that could essentially give them the NFC West title. The L.A. Chargers are also 10-point favorites against a division rival, but their game against the Oakland Raiders will come on the road. Oakland was the NFL’s worst team in the first half of the season.

The Indianapolis Colts, Tampa Bay Buccaneers and San Francisco 49ers are all favored by a field goal. No Week 10 point spread is less than three points.

A week after the L.A. Rams and New Orleans Saints totaled 80 points in their marquee matchup, Week 10 features the year’s lowest total. The total for Buffalo’s road game against the New York Jets is just 37 points. The Bills and Jets scored 15 total points in Week 9.

The Saints and Cincinnati Bengals have the highest total of Week 10. New Orleans is one of four road favorites after handing the Rams their first loss of the season.

Below are the available betting lines for all the Week 10 games, including the point spreads and totals. These are the consensus odds from multiple sportsbooks in Las Vegas and online, via OddsShark.

Thursday, Nov. 8

Carolina Panthers (+4) at Pittsburgh Steelers, 51.5

Sunday, Nov. 11

Detroit Lions (+6.5) at Chicago Bears, 45

Arizona Cardinals (+16.5) at Kansas City Chiefs, 50

New England Patriots (-7) at Tennessee Titans, 46.5

New Orleans Saints (-4.5) at Cincinnati Bengals, 54

Atlanta Falcons (-4) at Cleveland Browns, 51

Jacksonville Jaguars (+3) Indianapolis Colts, 47

Washington Redskins (+3) at Tampa Bay Buccaneers, 51.5

Buffalo Bills (+7.5) at New York Jets, 37

Los Angeles Chargers (-10) at Oakland Raiders, 50.5