NFL 2019 Week 2 Lines: Point Spreads, Betting Odds From Las Vegas, Online Sportsbooks

Tom Brady Patriots Super Bowl — Tom Brady #12 of the New England Patriots passes against the Philadelphia Eagles during Super Bowl Lll at U.S. Bank Stadium on February 4, 2018 in Minneapolis, Minnesota. Jonathan Daniel/Getty Images

More than half the league is looking to pick up their first victory of the 2019 NFL season in Week 2. The early betting odds indicate that a few of those winless teams aren’t expected to even come close to getting in the win column.

The New England Patriots are massive road favorites against the Miami Dolphins, laying three scores in a matchup with their AFC East rivals. After beating Miami by 49 points, the Baltimore Ravens are favored by nearly two touchdowns against the Arizona Cardinals.

The Houston Texans and Kansas City Chiefs are both favored by more than two points against division rivals. Kansas City is one of seven road favorites. The point spread between the Chicago Bears and Denver Broncos is a pick’em, meaning only half of the home teams in Week 2 are favored.

Two road teams are favored in primetime. That includes “Monday Night Football,” where the Cleveland Browns are laying 2.5 points against the New York Jets. Baker Mayfield and Cleveland were blown out by 30 points at home in the season opener.

The Buffalo Bills are looking to win their second game at MetLife Stadium within the span of a week. Buffalo is laying two points to the New York Giants after recording a comeback victory over the Jets in Week 1.

Denver and Chicago have the lowest Week 2 total. The two teams scored a combined 19 points in Week 1.

The New Orleans Saints and Los Angeles Rams have the highest Week 2 total in a rematch of the 2019 NFC Championship Game. The Saints and Rams had the conference’s two highest-scoring teams last season.

Below are the complete betting lines for all the Week 2 games, including the point spreads and totals. These are the consensus odds from multiple sportsbooks in Las Vegas and online, via OddsShark.

Thursday, Sept. 12

Tampa Bay Buccaneers (+6.5) at Carolina Panthers, 49.5

Sunday, Sept. 15

Minnesota Vikings (+2.5) at Green Bay Packers, 44.5

Jacksonville Jaguars (+9) at Houston Texans, 43.5

Indianapolis Colts (+3) at Tennessee Titans, 44

Arizona Cardinals (+13.5) at Baltimore Ravens, 46.5

San Francisco 49ers (+1) at Cincinnati Bengals, 44.5

Los Angeles Chargers (-2.5) at Detroit Lions, 47.5

New England Patriots (-18.5) at Miami Dolphins, 47.5

Buffalo Bills (-2) at New York Giants, 43.5

Seattle Seahawks (+3.5) at Pittsburgh Steelers, 46.5