Tom Brady Patriots Eagles
Tom Brady #12 of the New England Patriots attempts to throw a pass under pressure from Derek Barnett #96 of the Philadelphia Eagles during the fourth quarter in Super Bowl LII at U.S. Bank Stadium on Feb. 4, 2018 in Minneapolis. Patrick Smith/Getty Images

The New England Patriots and Kansas City Chiefs look to be in a class of their own, becoming the NFL’s only teams to get off to a 4-0 start after meeting in the 2019 AFC Championship Game. Their dominance is reflected in the Week 5 betting odds as two of the biggest favorites on the schedule.

New England laying at least two touchdowns for the third time this season. The winless Washington Redskins are 15.5-point underdogs at home against the defending champions. Kansas City is favored by 11 points over the Indianapolis Colts on “Sunday Night Football.”

The Philadelphia Eagles are the only other double-digit favorite in Week 5. They are laying 14 points against the visiting New York Jets, who don’t yet know if Sam Darnold will be back under center.

“Thursday Night Football” features the week’s smallest point spread. The Seattle Seahawks are giving two points to the Los Angeles Rams. Both teams are 3-1 before their pivotal NFC West matchup.

The San Francisco 49ers sit atop the NFC West as the only team in the conference with a perfect record. Jimmy Garoppolo and Co. are 3.5-point favorites over the first-place Cleveland Browns on “Monday Night Football.”

Cleveland owns the early tiebreaker with the Baltimore Ravens atop the AFC North. The Pittsburgh Steelers can move past Baltimore in the division with a win Sunday afternoon, though the Ravens are four-point favorites at Heinz Field.

The Dallas Cowboys are 3.5-point favorites over the Green Bay Packers in what might be the best game of the week. Ten of the 15 games in Week 5 feature a betting line between three and five points.

The London game between the Chicago Bears and Oakland Raiders is included in that group. Chicago is laying 4.5 points against Oakland with Chase Daniel at quarterback.

Below are the complete betting lines for all the Week 5 games, including the point spreads and totals. These are the consensus odds from multiple sportsbooks in Las Vegas and online, via OddsShark.

Thursday, Oct. 3

Los Angeles Rams (+2) at Seattle Seahawks, 49

Sunday, Oct. 6

Atlanta Falcons (+5) at Houston Texans, 48.5

Tampa Bay Buccaneers (+3) at New Orleans Saints, 47

Buffalo Bills (+3) at Tennessee Titans, 38.5

Jacksonville Jaguars (+3.5) at Carolina Panthers, 41

Arizona Cardinals (+4.5) at Cincinnati Bengals, 48

Minnesota Vikings (-4.5) at New York Giants, 45

New York Jets (+14) at Philadelphia Eagles, 44.5

Baltimore Ravens (-4) at Pittsburgh Steelers, 42.5

New England Patriots (-15.5) at Washington Redskins, 43.5

Chicago Bears (-4.5) at Oakland Raiders, 41

Denver Broncos (+6.5) at Los Angeles Chargers, 44.5

Green Bay Packers (+3.5) at Dallas Cowboys, 46.5

Indianapolis Colts (+11) at Kansas City Chiefs, 57

Monday, Oct. 7

Cleveland Browns (+3.5) at San Francisco 49ers, 46.5