NFL 2022 Week 3 Lines: Point Spreads, Betting Odds, Schedule

An early look at the early NFL Week 3 lines shows no point spreads of more than a touchdown. Half of the home teams on the upcoming schedule are underdogs as some of the top contenders for the 2022 season hit the road.

The betting odds favor the Kansas City Chiefs by 6.5 points against the Indianapolis Colts, which have been made the biggest home underdogs on the Week 3 schedule. The Colts are winless after a pair of divisional games to start the season. Indianapolis entered Week 1 as the odds-on favorite to win the AFC South.

The Cincinnati Bengals have arguably been the most disappointing team to start the season, losing consecutive games as heavy betting favorites. The Bengals are early 4.5-point favorites for their matchup with the New York Jets at MetLife Stadium. Cincinnati is coming off a Week 2 loss against Cooper Rush and the Dallas Cowboys.

The Los Angeles Chargers and Minnesota Vikings are tied as the biggest Week 3 favorites. Los Angeles is laying a touchdown against the Jacksonville Jaguars, though Justin Herbert's status is not completely clear because of a rib injury. The Vikings conclude the Week 2 schedule with a game against the Philadelphia Eagles on "Monday Night Football."

Ahead of their Monday night contest against the Tennessee Titans, the Buffalo Bills are 4.5-point road favorites against the Miami Dolphins. Miami was as impressive as anyone in Week 2 with a 42-38 victory over the Baltimore Ravens. Tua Tagovailoa led the Dolphins to a comeback win with 469 passing yards and six touchdowns.

The Ravens are three-point road favorites against the New England Patriots. The Patriots have scored 24 points through two games.

The Cleveland Browns are favored by more than a field goal over the Pittsburgh Steelers on "Thursday Night Football." The New York Giants are favored by exactly a field goal against Dallas on "Monday Night Football."

Here are the complete betting lines for all the Week 3 games, including the point spreads and totals, via FanDuel Sportsbook.

Thursday, Sept. 22

Pittsburgh Steelers (+3.5) at Cleveland Browns, 40

Sunday, Sept. 25

Baltimore Ravens (-3) at New England Patriots, 44

Buffalo Bills (-4.5) at Miami Dolphins, 51.5

New Orleans Saints (-3) at Carolina Panthers, 40.5

Detroit Lions (+7) at Minnesota Vikings, 51.5

Kansas City Chiefs (-6.5) at Indianapolis Colts, 49.5

Philadelphia Eagles (-4) at Washington Commanders, 50.5

Las Vegas Raiders (-1) at Tennessee Titans, 45.5

Houston Texans (+2.5) at Chicago Bears, 39.5