NFL Playoff Picks Against The Spread 2022: Predictions ATS For Divisional Games, Second-Round Odds

After a bunch of one-sided games on Wild-Card Weekend, the divisional round of the 2022 NFL playoffs is expected to be much more competitive. No team is favored by a touchdown. Two of the underdogs beat their divisional opponent in the regular season.

Here are picks against the spread for all the second-round playoff games. Betting odds come from FanDuel Sportsbook.

Cincinnati Bengals (+3.5) at Tennessee Titans

The Titans earned the No. 1 seed for a reason, and Tennessee can take care of business at home behind an underrated defense. It won’t be easy, however, and there’s a good chance this is a very close game that’s decided by a field goal. Half of Tennssee’s 12 regular-season victories were decided by three points or fewer. Four of Cincinnati’s six losses with Joe Burrow under center came by no more than a field goal. Burrow gives the Bengals the best quarterback in this game. It’s unknown what the Titans will get from Derrick Henry, who is trying to play for the first time in 12 weeks.

Prediction ATS: Cincinnati

San Francisco 49ers (+5.5) at Green Bay Packers

Green Bay had a major advantage by not playing in the wild-card round. While Packers’ defensive stars Jaire Alexander and Za'Darius Smith had one more week to recover as they return from injuries, Jimmy Garoppolo and Fred Warner were banged up in a hard-fought win over the Dallas Cowboys. Garoppolo had another pedestrian playoff performance. The quarterback has not thrown for more touchdowns than interceptions or 220 yards in four postseason games. That won’t be enough to beat MVP favorite Aaron Rodgers and Green Bay’s top-10 defense at Lambeau Field. The Packers beat the 49ers 30-28 on the road in Week 3.

Prediction ATS: Green Bay

Los Angeles Rams (+3) at Tampa Bay Buccaneers

It’s hard to bet against Tom Brady and the defending champs as field-goal favorites against an inferior team. Yes, the Rams beat the Buccaneers in Week 4 and Tampa Bay is dealing with injuries on the offensive line. But the Bucs are also healthier in the secondary than they were in their loss to L.A., while Los Angeles didn’t have its starting safeties in the wild-card round. Matthew Stafford had 11 interceptions in nine regular-season road games. Stafford had a triple-digit passer rating in less than half of those matchups. He probably won’t be able to match the greatest quarterback of all time Sunday.

Prediction ATS: Tampa Bay

Buffalo Bills (+2.5) at Kansas City Chiefs

The Chiefs blew out the Bills in the 2021 AFC Championship Game. Buffalo dominated Kansas City in Week 5 this season. Both contests were aberrations, and Sunday’s playoff matchup should be much closer. Josh Allen was nearly perfect in the first round. Don’t expect that to be the case against a Chiefs’ defense that allowed the fewest points in the NFL after that regular-season loss to the Bills. Patrick Mahomes’ 105.1 passer rating in nine career playoff games and a much-improved Kansas City pass defense makes the Chiefs the best bet.

Prediction ATS: Kansas City