NFL Sunday Predictions Week 10: Full TV Schedule And What To Expect

There are plenty of interesting matchups in Week 10. Sunday's games offer an AFC West showdown of San Diego hosting Denver, Green Bay learning how to adjust without Aaron Rodgers, the New York Giants looking to stay afloat in the NFC East, Cincinnati trying to bury defending champion Baltimore, and Detroit seeking the inside track for the NFC North.

Byes: Cleveland, Kansas City, New England, N.Y. Jets.

Jacksonville +13.5 at Tennessee -13.5

The Titans are a game out of the final AFC Wild Card and two out of the AFC South lead after snapping their three-game slide. Sunday will be the first game against division rival and winless Jacksonville. But if the Jaguars can avoid falling behind early, Maurice Jones-Drew could finally bust out against Tennessee’s 26th ranked rushing defense.

Time: Sunday, 1 p.m. E.T.

Channel: CBS

Prediction: Tennessee 30, Jacksonville 13

Philadelphia +10 at Green Bay -10

Lambeau in November and an Eagles squad that’s given up the most total offensive yards in the league are reason enough for the Packers to be 10 point favorites, even with Rodgers out for the foreseeable future with a fractured collarbone. Philly’s Nick Foles did tie the NFL record of seven touchdowns in a single game in Week Nine, which should have Green Bay faithful worried. Eddie Lacy will be the focal point of the offense, and Green Bay will try to limit turnovers and Philadelphia’s possession.

Time: Sunday, 1 p.m. E.T.

Channel: FOX

Prediction: Green Bay 24, Philadelphia 20

Buffalo +3 at Pittsburgh -3

Pittsburgh put up a season-high 31 points and Ben Roethlisberger threw four or more touchdowns for just the third time in six years, and it still wasn’t enough. The Bills have lost four of their last five, but just put up 241 rushing yards against the NFL’s best defense in Kansas City. This should be a very slow game, that will likely come down to turnovers.

Time: Sunday, 1 p.m. E.T.

Channel: CBS

Prediction: Pittsburgh 20, Buffalo 17

Oakland +5.5 N.Y. Giants -5.5

Fresh off a bye week and still in the thick of the NFC East, New York has won five straight after a week off. The Raiders were burned by seven passing touchdowns from Philadelphia, and quarterback Terrelle Pryor is day-to-day with an injured knee. Pryor has also thrown four picks to no touchdowns in Oakland’s last two games. His health and how well the Giants secondary of Prince Amukamara and Antrel Rolle play will determine the outcome.

Time: Sunday, 1 p.m. E.T.

Channel: CBS

Prediction: N.Y. 34, Oakland 20

St. Louis +11 at Indianapolis -11

The Colts and Andrew Luck still put up points with receiver Reggie Wayne out, but the quarterback’s accuracy (18-for-40 in Week Nine, and 55.3 percent this season), should be of concern against the Rams ninth ranked pass defense and a pass rush that’s tied for third in the NFL with 29.0 sacks. St. Louis will need another breakout performance from rookie running back Zac Stacy (127 yards 2 TDs in Week Nine) in order to keep up with Indy. The Rams have only scored 20 or more points in four games and are 23 rd in the league with 20.7 ppg.

Time: Sunday, 1 p.m. E.T.

Channel: FOX

Prediction: Indianapolis 35, St. Louis 20

Seattle -7 at Atlanta +7

In a rematch of one of last season’s NFC Divisional round games, Seattle has been one of the NFL’s best all-around teams and got a boost of confidence after coming back to force overtime and beat Tampa Bay. The 2-6 Falcons technically aren’t out of the playoff race, but surrendering 27.3 ppg and a rushing offense that’s last in the NFL won’t pull them out of the doldrums anytime soon.

Time: Sunday, 1 p.m. E.T.

Channel: FOX

Prediction: Seattle 27, Atlanta 20

Cincinnati -2 at Baltimore +2

The Bengals became just the third team to lose by a safety in overtime in NFL history, but were playing like Super Bowl contenders before that. Baltimore just lost to Cleveland for the first time in Joe Flacco’s career, and haven’t been able to kick start the offense during its three-game losing streak. Unless Ray Rice can bust out of his 2.7 yards per carry slump, Cincinnati will take the Ravens out of the AFC North race.

Time: Sunday, 1 p.m. E.T.

Channel: CBS

Prediction: Cincinnati 17, Baltimore 13

Detroit -2.5 at Chicago +2.5

The NFC North is arguably the toughest division in the NFL right now, and a second loss to Detroit could take Chicago out of the division chase. The Lions will be rested off a bye, and the Bears will be on a short week after pulling out their first win without Jay Cutler with 442 total offensive yards. How well Chicago’s defensive front attacks Detroit quarterback Matthew Stafford will be the key matchup. The Bears recorded 5.0 sacks against Green Bay in Week Nine, after only earning more than one sack in one other game this season, a 40-23 win over Pittsburgh. Stafford’s been sacked 10 times this season, the best mark in the NFL.

Time: Sunday, 1 p.m. E.T.

Channel: FOX

Prediction: Detroit 30, Chicago 24

Carolina +6.5 San Francisco -6.5

Other than Kansas City, the only teams with longer win streaks are Carolina (4), Seattle (4), and San Francisco (5). Both the Panthers and 49ers field two of the NFL’s best defenses, but they’ve also feasted on the worst teams in the league. Carolina has beaten teams with a combined 6-27 record, and San Francisco’s opponents went 13-28. Sunday will be the first true test for both squads, but especially for Cam Newton, who’s led Carolina to four straight games of 30 or more points. How well the 49ers force Newton into mistakes will determine the outcome.

Time: Sunday, 4:05 p.m. E.T.

Channel: FOX

Prediction: San Francisco 36, Carolina 33

Houston +2.5 at Arizona -2.5

The Texans have lost six straight, currently the second worst run in the league, but Case Keenum looked sharp in the Week Nine loss to Indy. Keenum could have another big game versus an Arizona secondary that’s 24th overall. Same goes for Houston’s secondary against Carson Palmer, who’s thrown the second most interceptions this season (14). The Texans will end their slide in a very close game.

Time: Sunday, 4:25 p.m. E.T.

Channel: CBS

Prediction: Houston 24, Arizona 20

Denver -7 at San Diego +7

Maybe the biggest game of the week, and most important this early in the season for both Denver and San Diego. The Chargers face Denver and Kansas City twice in the last eight weeks, and could seriously disrupt both clubs’ playoff hopes in the process. Denver needs a win to keep pace with Kansas City ahead of Week 11’s AFC West showdown at Mile High. The Chargers defense looked gassed in the overtime loss to Washington, and will have to find a way to shutdown Knowshon Moreno in order to have any chance.

Time: Sunday, 4:25 p.m. E.T.

Channel: CBS

Prediction: Denver 37, San Diego 27

Dallas +7 at New Orleans -7

Tony Romo actually led a fourth quarter comeback in Week Nine, and the Cowboys have a comfortable two game lead in the NFC East. But Dallas’s pass defense is 31st in the league, and Drew Brees has thrown for 300-plus yards in six of eight games this year. The Saints are coming off a disappointing loss to the N.Y. Jets where Brees was pressured throughout and threw two interceptions. If DeMarcus Ware makes his return from a thigh injury, the Cowboys could pull out the victory.

Time: Sunday, 8:30 p.m. E.T.

Channel: NBC

Prediction: Dallas 34, New Orleans 30