NFL Week 15 Picks Against The Spread 2016: Predictions, Updated Las Vegas Odds For Every Game ATS

Week 15 of the 2016 NFL season features the year’s biggest betting lines with two teams favored by at least two touchdowns. Favorites went 11-5 against the spread in Week 14, and they have a good chance to cover a few large point spreads in Week 15.

Just a few days after firing their head coach, the Los Angeles Rams are 15-point underdogs. Having not won since they beat the Rams in the season opener, the San Francisco 49ers are getting 14 points in their visit to Atlanta. The winless Cleveland Browns are also double-digit underdogs.

Below are picks against the spread for every game in Week 15, as well as updated betting odds at Las Vegas and online sportsbooks. Betting lines and trends are courtesy of OddsShark.

Los Angeles Rams (+15) at Seattle Seahawks

Betting on a 15-point favorite usually isn’t a smart move, but the Rams will have trouble keeping Thursday’s game close. They’ve lost three straight games by at least 16 points, and L.A. is 0-6-1 against the spread in their last seven games as underdogs. Seattle is extremely dangerous at home, and Jared Goff will have a long night against one of the NFL’s best secondaries.

Prediction ATS: Seattle

Miami Dolphins (-2.5) at New York Jets

The drop off from Ryan Tannehill to Matt Moore won’t be enough for the Jets to compete with a potential playoff team. Moore is still better than Bryce Petty, who hasn’t posted a passer rating better than 75.5 in three games as the Jets’ primary quarterback. New York needed overtime to beat the one-win 49ers last week, and Saturday's game shouldn’t be particularly close.

Prediction ATS: Miami

Detroit Lions (+4.5) at New York Giants

Nearly all of New York’s and Detroit’s games have been decided in the final minutes, so Sunday’s contest should come right down to the wire. Matthew Stafford's finger injury could be an issue against a defense that keeps getting better, but New York’s offensive struggles are the reason five of their nine wins have come by four points or less.

Prediction ATS: Detroit

Philadelphia Eagles (+6) at Baltimore Ravens

Carson Wentz hasn’t had a passer rating better than 86.7 since Oct. 30, and that won’t change against the league’s No. 4 ranked defense. The Eagles have nothing to play for, and this game could get ugly if the Ravens take a two-score lead at any point.

Prediction ATS: Baltimore

Green Bay Packers (-6.5) at Chicago Bears

Aaron Rodgers is back to playing like an MVP candidate, having thrown 10 touchdown passes and no interceptions in the last four games. He’ll have another big game in Chicago against a team in which Green Bay has covered the spread 10 of the last 12 times.

Prediction ATS: Green Bay

Indianapolis Colts (+4) at Minnesota Vikings

Minnesota’s defense remains one of the NFL’s best, but the unit needs to be at its best every week in order for the Vikings to win. Only the Rams rank worse in total offense than the Vikings, and Minnesota could suffer an upset if Andrew Luck plays well.

Prediction ATS: Indianapolis

Cleveland Browns (+10) at Buffalo Bills

The Browns are not only winless, but they have stopped being competitive. Cleveland hasn’t come close to covering the spread in their last five games, and they’ll be hard-pressed to keep Sunday’s game within single digits. Buffalo is 10th in the NFL in scoring, and the Browns haven’t scored more than 13 points in a game since Week 8.

Prediction ATS: Buffalo

Tennessee Titans (+5.5) at Kansas City Chiefs

The Chiefs might be the biggest threat to the Patriots in the AFC, but they haven’t exactly been winning in dominant fashion. Their last five wins have come by five points or fewer, and Kansas City is 0-6 against the spread in their last six games as favorites of five points or more. Tennessee has the NFL’s No.3 rushing attack, and DeMarco Murray could have a big day against a defense that ranks 27th against the run.

Prediction ATS: Tennessee

Jacksonville Jaguars (+6) at Houston Texans

Houston has trouble defeating good teams, but they take care of the bad teams on their schedule. They are 7-0-1 against the spread in their last eight games as a favorite, including a win in Jacksonville earlier this year. Blake Bortles is one of the league’s worst quarterbacks, and he’ll have trouble moving the ball against a top-five pass defense.

Prediction ATS: Houston

New Orleans Saints (+2.5) at Arizona Cardinals

As good as the Saints’ offense has looked on its best days, the unit has struggled to score against good defenses. New Orleans has totaled just 24 points in consecutive losses to Detroit and Tampa Bay, and Arizona has allowed fewer points than any NFL team.

Prediction ATS: Arizona

San Francisco 49ers (+14) at Atlanta Falcons

This game has “blowout” written all over it. Atlanta is the NFL’s top scoring team, and they could approach 50 points against San Francisco’s defense, which ranks dead last in the league. Colin Kaepernick and the 49ers’ offense aren't good enough to come close to keeping pace with Matt Ryan and Co.

Prediction ATS: Atlanta

New England Patriots (-3) at Denver Broncos

Denver might miss the playoffs because of their difficult schedule, but they aren’t out of postseason contention just yet. The Broncos have beaten the Patriots three times in Denver since 2014, even winning last year with Brock Osweiler at quarterback. Trevor Siemian has actually played fairly well this season, and he could have some success against New England’s defense.

Prediction ATS: Denver

Oakland Raiders (-3) at San Diego Chargers

San Diego nearly won in Oakland earlier this year, and they have a good chance to get revenge against the Raiders at home. Derek Carr seemed to be affected by his injured finger last week when he threw for just 117 yards, and the Raiders won’t win if they can’t put up a lot of points. The Chargers are fourth in the NFL with 26.9 points per contest.

Prediction ATS: San Diego

Pittsburgh Steelers (-3) at Cincinnati Bengals

Pittsburgh continues to play like a Super Bowl contender, winning four straight games by at least a touchdown. Le’Veon Bell might have a field day against a Cincinnati defense that allows 4.5 yards per carry.

Prediction ATS: Pittsburgh

Tampa Bay Buccaneers (+7) at Dallas Cowboys

Dallas’ offense has stalled in the last few games, and things don’t get any easier against a defense that’s allowing less than 13 points per game during their five-game winning streak. The Cowboys should bounce back with a win at home, but the betting line is probably a point too high.

Prediction ATS: Tampa Bay

Carolina Panthers (+4.5) at Washington Redskins

Aside from Carolina’s 33-point loss in Seattle two weeks ago, the Panthers have lost a lot of close contests against good teams. They were defeated by three points or less by the Broncos, Buccaneers, Raiders and Chiefs, and the Redskins might join the list Monday night.

Prediction ATS: Carolina

Season Record: 108-94-6​