NFL Week 17 Picks Against The Spread 2022: Predictions ATS, Odds, Upset Winners

Almost all of the games on the NFL Week 17 schedule have playoff implications. Four teams that are outside of the latest playoff picture but are vying for wild-card spots are favored Sunday. Seven games feature a point spread of a field goal or less.

Here are picks against the spread for every game in Week 17 and updated betting odds from FanDuel and DraftKings Sportsbook.

Tennessee Titans (+10) at Dallas Cowboys

Dallas should win this game by two touchdowns. There's a good chance that Derrick Henry won't play because of a hip injury. Tennessee has its eyes on an unofficial AFC South title game with Jacksonville in the season finale. Malik Willis has thrown for 232 yards, no touchdowns and three interceptions in three starts.

Prediction ATS: Dallas

Carolina Panthers (+3) at Tampa Bay Buccaneers

Tampa Bay's offense struggles against every opponent, and that's unlikely to change against this Carolina defense. The Panthers are 4-2 in their last six games, giving up an average of 18.2 points during that stretch. The Buccaneers have a bottom-five scoring offense. Carolina already beat Tampa Bay 21-3 earlier this season.

Prediction ATS: Carolina

Cleveland Browns (+2.5) at Washington Commanders

Maybe Cleveland's offense will get back on track next year when Deshaun Watson has spent more time with the team, but the quarterback still looks like someone who missed nearly two years of football. The Browns have been limited to one offensive touchdown or fewer in all four of Watson's starts. Washington is fourth in total defense.

Prediction ATS: Washington

New Orleans Saints (+6.5) at Philadelphia Eagles

With the Eagles still trying to clinch the NFC East title and a first-round bye, Jalen Hurts might return to the field in Week 17. That would be bad news for the Saints, which have stayed in the playoff hunt by defeating below-average quarterbacks. New Orleans has given up 30 points per game in three matchups with 2022 Pro Bowl quarterbacks. Philadelphia is the league's top-scoring offense.

Prediction ATS: Philadelphia

Arizona Cardinals (+3.5) at Atlanta Falcons

This is the only game in the Week 17 schedule featuring a pair of teams that have been eliminated from playoff contention. The Cardinals can pull off the upset after nearly beating Tom Brady and the Bucs on Christmas Day. The Falcons are 1-6 in their last seven games.

Prediction ATS: Arizona

Jacksonville Jaguars (-4) at Houston Texans

Sunday's game is essentially meaningless for Jacksonville. The AFC South championship will be on the line when the Jaguars meet the Titans in Week 18, regardless of what happens in Week 17. One of Houston's two victories this season came against Jacksonville. The Texans have a nine-game winning streak against the Jaguars.

Prediction ATS: Houston

Chicago Bears (+5.5) at Detroit Lions

Detroit's Week 16 loss in Carolina was an aberration. The Lions were 6-1 in their last seven games, largely facing quality opponents, before losing against the Panthers. The Bears are on an eight-game losing streak and headed for a top-two draft pick. Detroit can make the playoffs by winning its final two games.

Prediction ATS: Detroit

Miami Dolphins (+2.5) at New England Patriots

Even if Teddy Bridgewater has to start in place of Tua Tagovailoa, the Dolphins will arguably have the better quarterback in this game. Miami will certainly have the better playmakers and offensive coaches in New England. The Dolphins beat the Patriots 20-7 in Week 1. New England is giving up 24.4 points per game over the last five contests.

Prediction ATS: Miami

Denver Broncos (+13.5) at Kansas City Chiefs

The Broncos have little chance to pull off the outright upset. Denver is 1-5 in its last six games. Kansas City's only loss in the last nine games was a nail-biter in Cincinnati. The Chiefs jumped out to a 27-0 lead in Denver a few weeks ago before winning 34-28. If Kansas City jumps out to another big lead, the Broncos' last-ranked scoring offense is unlikely to mount a comeback on the road.

Prediction ATS: Kansas City

Indianapolis Colts (+4.5) at New York Giants

Since winning his debut, Jeff Saturday is 0-5 as the Colts head coach. Indianapolis scored fewer than 20 points in four of those defeats, and the Colts blew the biggest lead in league history in the other contest. New York is susceptible against the run, but Indianapolis is without star running back Jonathan Taylor. The Giants should beat the Colts and clinch a spot in the playoff picture.

Prediction ATS: New York

New York Jets (-2.5) at Seattle Seahawks

With Mike White back under center, the Jets should win this game and stay alive in the playoff race. Tyler Lockett's absence should allow Sauce Gardner to blanket DK Metcalf and shut down Seattle's passing attack. New York has the league's No. 3 defense. The Seahawks' 29th ranked defense has given up more than 20 points in seven straight games.

Prediction ATS: New York

San Francisco 49ers (-6) at Las Vegas Raiders

Keep picking the 49ers until they lose. San Francisco is on an eight-game winning streak with a 7-1 record against the spread during that stretch. Opponents are averaging 12.1 points per game against the 49ers' No. 1 ranked defense in the last eight games. The Raiders have one win against teams that are in the Week 17 playoff picture.

Prediction ATS: San Francisco

Minnesota Vikings (+3) at Green Bay Packers

The Packers haven't been overly impressive while keeping their playoff hopes alive. Green Bay has been outgained twice during its three-game winning streak. Aaron Rodgers is only averaging 216.3 passing yards with three touchdowns and two interceptions in those contests. Justin Jefferson had nine catches for 184 yards in Minnesota's 23-7 win over Green Bay in Week 1.

Prediction ATS: Minnesota

Los Angeles Rams (+6.5) at Los Angeles Chargers

Now that the Chargers have clinched a wild-berth, they have nothing on the line in Week 17. The Rams seem to still be motivated, blowing out the Broncos 51-14 on Christmas. Baker Mayfield is looking to prove that he can be a quality starting quarterback in 2023. Mayfield is 2-1 as the Rams' starter.

Prediction ATS: Los Angeles Rams

Pittsburgh Steelers (+3) at Baltimore Ravens

Expect this to be another low-scoring battle that is decided by a field goal or less, similar to Baltimore's 16-14 win in Pittsburgh a few weeks ago. In the four weeks since Lamar Jackson got hurt, the Ravens have failed to score more than 17 points in a single game. The Steelers are 6-2 when T.J. Watt plays, giving up 20 points or fewer in all but one of those contests.

Prediction ATS: Pittsburgh

Buffalo Bills (-1.5) at Cincinnati Bengals

An argument can be made that Cincinnati should be favored in this matchup. The Bengals' seven-game winning streak includes a victory against the Chiefs at home. Joe Burrow is playing as well as Josh Allen. Cincinnati's defense is one of the league's most underrated units.. The Bengals can pull off the upset and stay in contention for the AFC's No. 1 seed.

Prediction ATS: Cincinnati

Season Record: 113-122-4