NFL Week 3 Odds: Line Changes For Steelers, Colts, Raiders, Bucs, Other Games Amid Injury News

The betting odds for several games on the NFL Week 3 schedule have seen notable changes over the last few days. The line for a handful of matchups has shifted by at least a full point since Monday morning and quarterback injury updates have resulted in additional point spread changes.

The line movement starts with the first game of Week 3. The Carolina Panthers are favored by eight points at FanDuel Sportsbook against the Houston Texans in light of Tyrod Taylor being ruled out. Houston was a seven-point home underdog when it appeared likely that Taylor would be replaced by Davis Mills because of a hamstring injury.

Indianapolis Colts quarterback Carson Wentz and Miami Dolphins signal-caller Tua Tagovailoa both finished Week 2 on the sidelines. Wentz’s injury is more serious than initially known, while Miami received encouraging news about Tagovailoa. The updates are reflected in both betting lines.

Colts’ HC Frank Reich said QB Carson Wentz sprained both ankles and it’s too early to tell what his status is for Sunday at Tennessee.
— Adam Schefter (@AdamSchefter) September 20, 2021

Indianapolis has gone from a 4.5-point underdog to a 5.5-point underdog in Tennessee. It’s been reported that Wentz is dealing with two sprained ankles, increasing the likelihood that the Colts will give Jacob Eason his first NFL start.

Miami learned that there weren't any major issues with Tagovailoa’s bruised ribs. The Dolphins are getting 3.5 points in Las Vegas after initially being named 4.5-point underdogs against the Raiders.

The odds for the matchup between the Pittsburgh Steelers and Cincinnati Bengals have moved a few times. When Ben Roethlisberger’s status became somewhat unclear because of a left pectoral injury, the line dropped a full point to 3.5. The line briefly moved back up to four points, but Pittsburgh is now favored by just a field goal at home.

#Steelers QB Ben Roethlisberger has a left pec injury. Coach Mike Tomlin says it will affect his preparation ability - and "We'd better be ready to be adjustable."
— Aditi Kinkhabwala (@AKinkhabwala) September 21, 2021

The biggest change has come in the marquee afternoon game, though not because of any quarterback injury. The Tampa Bay Buccaneers opened as 1.5-point road underdogs against the Los Angeles Rams. Tampa is now favored by 1.5 points, having won 10 straight games, including last season’s Super Bowl run.

There are five road favorites in Week 3.