The top after-market NASDAQ stock market gainers are: Exelis, MannKind, Velti, Amarin and LM Ericsson. The top after-market NASDAQ stock market losers are: Hot Topic, Amtech Systems, Flow International, Idenix Pharma and Spectrum Pharma.

Gainers:

Biotechnology company Exelixis, Inc. (NASDAQ:EXEL) shares gained 5.85 percent, or 25 cents, to $4.52. The company recently said an early-stage study showed that 40 mg of cabozantinib resulted in high rates of bone scan response in patients with metastatic castration-resistant prostate cancer.

Shares of MannKind Corp. (NASDAQ:MNKD) 4.92 percent, or 15 cents, to $3.20 on a volume of 202,979 shares.

Shares of Velti PLC (NASDAQ:VELT) advanced 4 percent, or 35 cents, to $9.10 after it announced the acquisition of Mobile Interactive Group, the UK's largest mobile marketing company. The acquisition expands Velti's lead as the world's largest mobile marketing company based on revenue, customers, consumer reach and technology holdings.

Amarin Corp. PLC (NASDAQ:AMRN) shares improved 3.33 percent, or 24 cents, to $7.44 after the biopharmaceutical company said its AMR101 reduced both total and small low-density lipoprotein (LDL) particle concentration. The results are not only consistent with its known effects in decreasing apo-B and lack of LDL-cholesterol raising in patients with very high triglyceride levels but also is suggestive of another potentially favorable lipid effect.

LM Ericsson Telephone Co. (NASDAQ:ERIC) shares gained 2.64 percent, or 27 cents, to $10.49.

Losers:

Shares of Hot Topic Inc. (NASDAQ:HOTT) fell 14.37 percent, or 97 cents, to $5.78. The company is expected to report its third-quarter results on Nov.16. Wall Street expects the company to earn 7 cents on revenue of $179.15 million, according to analysts polled by Thomson Reuters. The consensus revenue estimate of $179.15 million is a 2.2 percent drop from $183.22 million in the same quarter last year.

Amtech Systems Inc. (NASDAQ:ASYS) shares dropped 10.90 percent, or $1.13, to $9.24 after it said it is expecting a loss for the first quarter due to weak revenue and higher research and development costs.

Flow International Corp. (NASDAQ:FLOW) shares slipped 7.06 percent, or 19 cents, to $2.50 on a volume of 8,093 shares.

Shares of Idenix Pharmaceuticals Inc. (NASDAQ:IDIX) declined 6.99 percent, or 50 cents, to $6.65 after it said it plans to make a new offering of common stock. However, the company didn't announce how many shares it may sell. Idenix had 96.2 million shares on the market as of Oct. 24.

Spectrum Pharmaceuticals, Inc. (NASDAQ:SPPI) shares fell 4.68 percent, or 59 cents, to $12.02 on a volume of 74,366 shares.

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