The top pre-market NASDAQ stock market gainers are: Green Mountain Coffee Roasters, Human Genome Sciences, Semtech, Starbucks and Atrinsic. The top pre-market NASDAQ stock market losers are: Coldwater Creek, Peet's Coffee & Tea, Canadian Solar, ARM Holdings, and SIGA Technologies.

Gainers

Green Mountain Coffee Roasters Inc. (GMCR) stock jumped 26.49 percent to $55.20 in the pre-market trading, while Starbucks Corp. (SBUX) stock gained 6.40 percent to $36.75. Green Mountain Coffee Roasters has agreed with Starbucks to take on the fast-growing single-serve market. Starbucks and Green Mountain Coffee Roasters announced a strategic relationship for the manufacturing, marketing, distribution and sale of Starbucks and Tazo tea branded K-Cup portion packs for use in GMCR's Keurig Single-Cup brewing system.

The relationship will see Starbucks being the exclusive licensed super-premium coffee brand produced by Green Mountain for the Keurig Single-Cup Brewing System. Green Mountain will also make available the Tazo tea branded K-Cup portion packs through food, drug, mass, club, specialty and department store retailers throughout the U.S. and Canada beginning in the fall of 2011.

Further, The Starbucks K-Cup portion packs will be made available through Green Mountain's consumer-direct websites beginning in 2012. This will lead to Starbucks' premium coffees being conveniently available to Starbucks' loyal consumers whenever, wherever and however they want it, through the quality, convenience and consistent preparation of the Keurig Single-Cup Brewing system.

Human Genome Sciences Inc. (HGSI) stock climbed 11.25 percent to $28.57 in the pre-market trading, as FDA approves Benlysta for the treatment of adult patients with active, autoantibody-positive systemic lupus erythematosus who are receiving standard therapy. Benlysta is expected to be available to physicians and patients before the end of March 2011, and is reportedly anticipated to generate sales of $3 billion by 2015.

Benlysta, an investigational human monoclonal antibody drug, is being developed by Human Genome and GlaxoSmithKline (GSK) under a co-development and commercialization agreement entered into in 2006.The deal called for the two companies to share equally the phase 3/4 development costs, sales and marketing expenses, and profits of any product commercialized under the agreement.

Semtech Corp. (SMTC) stock increased 8.89 percent to $24.50 in the pre-market trading, as it guided first quarter earnings and revenue above Street view. The company expects first quarter adjusted earnings of 41 cents to 44 cents a share and sales of $117 million to $121 million, while Street predicts profit of 40 cents a share on revenue of $114.40 million.

Semtech posted fourth quarter adjusted earnings of $31 million or 47 cents a share, up from $18.9 million or 30 cents a share last year. Revenue rose 36.8 percent to $116.3 million. Analysts had expected profit of 41 cents a share on revenue of $113.29 million.

Atrinsic, Inc. (ATRN) stock rose 6.16 percent to $4.48 in the pre-market trading.

Losers

Coldwater Creek Inc. (CWTR) stock plummeted 14.09 percent to $2.50 in the pre-market trading, as its fourth quarter loss was wider than Street view. Loss widened to $37.04 million or $0.40 a share from $9.68 million or $0.11 a share last year. The latest quarter results included a non-cash charge of $2.9 million or $0.03 a share, related to certain retail store asset impairments, compared to $0.6 million or $0.01 a share last year. Sales fell 20.8 percent to $252.10 million. Analysts had expected a loss of $0.26 a share on revenue of $282.75 million.

We expect our sales trends to remain challenging in the near term and expect the first steps of improvement to come as our summer product begins to arrive in our stores, Coldwater Creek said in the conference call. The company also said it was not giving exact earnings or sales outlook at this time citing 'reduced visibility' regarding the timing of its efforts to turnaround its business.

Peet's Coffee & Tea Inc. (PEET) stock plunged 13.11 percent to $41.75 in the pre-market trading, as its competitors Green Mountain Coffee Roasters and Starbucks are taking on the fast-growing single-serve market with a strategic relationship.

Canadian Solar Inc. (CSIQ) stock tumbled 9.05 percent to $12.46 in the pre-market trading, as its fourth quarter earnings missed Street view. Profit was $25.54 million or 58 cents a share, compared to a loss of $15.6 million or 38 cents a share last year. Revenue rose to $452.7 million from $254.2 million. Analysts had expected profit of 65 cents a share on revenue of $417.56 million.

Canadian Solar said shipments for the quarter were 237 MW, including 10 MW relating to the delivery of systems kits, compared to shipments of 141 MW a year ago. The company said its sales growth reflects the continued success of its market diversification efforts, with sales to non-European markets accounting for 29 percent of revenue in the latest quarter, compared to 8 percent in the year-ago quarter.

For the first quarter, Canadian Solar expects shipments to be about level with the fourth quarter, despite seasonality caused by unfavorable weather conditions in both Europe and North America. For full year 2011, the company reiterated its previous guidance of shipments of about 1,200 MW to 1,300 MW.

ARM Holdings plc (ARMH) stock slid 5.84 percent to $25.95 in the pre-market trading.

SIGA Technologies, Inc. (SIGA) stock declined 5.69 percent to $14.42 in the pre-market trading. Loss for the fourth quarter was $13.58 million or 29 cents a share, compared to a profit of $2.45 million or 8 cents a share last year. Revenue declined to $3.06 million from $3.96 million. Analysts had expected profit of 3 cents a share on revenue of $10.03 million.

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