The top pre-market NASDAQ stock market gainers are: Zoran, SIGA Technologies, Mentor Graphics, First Financial Northwest, and Transition Therapeutics. The top pre-market NASDAQ stock market losers are: Clinical Data, Camtek, Silicon Motion Technology, China MediaExpress Holdings, and Banner.

Gainers

Shares of Zoran Corp. (ZRAN) advanced 21.24 percent to $11.30 in the pre-market session. British chipmaker CSR Plc agreed to buy Zoran for about $679 million. Zoran shareholder would receive 1.85 ordinary shares of CSR in the form of American Depositary Shares. As of last Friday, this entitlement represents a value of $13.03 per share of Zoran stock. After the deal closure, which is expected in the second quarter of 2011, Zoran shareholders will own about 35 percent of the enlarged CSR.

SIGA Technologies, Inc. (SIGA) stock jumped 20.61 percent to $13.75 in the pre-market trading. The Biomedical Advanced Research and Development Authority, a unit of the U.S. Department of Health and Human Services, has advised that it is issuing a new Request for Proposal, number 11-100-SOL-00007, seeking to procure 1.7 million courses of a smallpox antiviral. The Request for Proposal also proposes that the contract would contain an option to procure up to 12 million additional courses.

SIGA's Chief Executive Eric Rose, said, This new Request for Proposal confirms the Government's commitment to a robust biodefense and the procurement of meaningful, new medical countermeasures against the most serious biothreats. SIGA intends to respond to this Request for Proposal, and we believe that we are well positioned to meet the Government's needs.

Shares of Mentor Graphics Corp. (MENT) climbed 17.77 percent to $17.10 in the pre-market session. The company announced comprehensive support for Accellera's Universal Verification Methodology (UVM) across a broad range of products. Key technologies that support UVM include the Questa advanced functional verification platform, the Questa MVC Verification IP library, the Veloce emulation platform and the Certe Testbench Studio tool.

First Financial Northwest, Inc. (FFNW) stock increased 14.80 percent to $6.05 in the pre-market trading.

Transition Therapeutics Inc. (TTHI) stock gained 13.45 percent to $4.05 in the pre-market trading.

Losers

Clinical Data, Inc. (CLDA) stock plunged 7.96 percent to $31.20 in the pre-market session. Forest Laboratories, Inc. (FRX) has agreed to buy Clinical Data for $30.00 per share in cash plus contingent consideration of up to $6.00 per share that may be paid upon achievement of certain commercial milestones related to Viibryd. The transaction is expected to be completed in the second quarter of 2011.

Shares of Camtek Ltd. (CAMT) plunged 7.53 percent to $4.30 in the pre-market trading. Adjusted profit for the fourth quarter was $2.1 million or $0.07 per share, up from $0.5 million or $0.02 per share last year. Revenue rose 48 percent to $25.4 million. An analyst has expected profit of 9 cents a share on revenue of $24 million. The company expects maintaining its current levels of revenue, between $25 million and $27 million for first quarter of 2011.

Silicon Motion Technology Corp. (SIMO) stock declined 6.76 percent to $8 in the pre-market trading.

Shares of China MediaExpress Holdings, Inc. (CCME) decreased 4.65 percent to $13.75 in the pre-market session.

Banner Corp. (BANR) stock fell 4.40 percent to $2.39 in the pre-market trading.

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