U.S. stock index futures pointed to a lower open on Wall Street on Wednesday, with futures for the S&P 500 down 0.3 percent, Dow Jones down 0.2 percent and Nasdaq 100 down 0.2 percent at 5:15 a.m. EDT.

The euro held near a one-week low against the dollar on Wednesday on concerns over Greece's capacity to resolve its debt crisis after a media report the country wanted to renegotiate a joint EU-International Monetary Fund aid deal.

In earnings news, investors will watch second-quarter earnings from Family Dollar and Monsanto , while Bed Bath & Beyond is to report fourth-quarter figures. * On the M&A front, U.S. coal miner Peabody Energy may have to raise its bid for Macarthur Coal by around 10 percent after the Australian miner rejected its latest $3.27 billion offer.

Lawyers at a U.S. regulator plan to recommend that the government try to block Google's proposed acquisition of mobile advertising firm AdMob on antitrust grounds, a source familiar with the matter said.

Carmakers Renault , Nissan Motor Co Ltd <7201.T> and Daimler said they would swap stakes and jointly develop cars in a tie up to gain scale and share costs.

U.S. officials are bringing a new wave of suits against UBS clients ahead of the April 15 tax filing deadline, including accounts several times bigger than prior cases, sources familiar with the cases said on Tuesday.

European stocks fell 0.2 percent in early trade on Wednesday, led by heavyweight mining and banking shares, halting a two-session rally as renewed concerns over Greece's finances rattled investors.

Asian stocks neared 22-month highs on Wednesday as regional investors largely shrugged off festering worries about fiscal problems in Europe and focused on a recovery in the world economy.

Oil edged 0.3 percent lower on Wednesday after trading near 18-month highs around $87 as a larger-than-expected drop in U.S. gasoline stockps signaled fuel demand was rebounding with an improving economic outlook.

The S&P 500 and Nasdaq rose modestly on Tuesday as the banking sector got a lift from positive analyst comments, while minutes from the Federal Reserve's last meeting eased concern over rising rates.

The Dow Jones industrial average <.DJI> eased 0.03 percent, the Standard & Poor's 500 Index <.SPX> added 0.2 percent and the Nasdaq Composite Index <.IXIC> rose 0.3 percent.

(Reporting by Joanne Frearson, editing by Will Waterman)