After suffering their first loss of the season, freshman Davis Webb and the No. 15 Texas Tech Red Raiders host the No. 18 Oklahoma State Cowboys on Saturday night at Jones AT&T Stadium.

Both are two of the most balanced teams in the Big-12. Tech is second in points scored per game (39.8) and fourth in total defense. The Cowboys are third in points scored (38.9) and allowed (19.6). OSU holds an edge upfront, ranking first against the run (122.7).

Ranking 98th in the country, the Red Raiders don’t have much of a rushing game, with no running back gaining 60 or more yards in the last two weeks, according to the Lubbock Avalanche-Journal. In last week’s 38-30 loss to Oklahoma, rushers DeAndre Washington and Kenny Williams combined for 80 yards and one touchdown on 17 carries.

Instead quarterback Webb has fired off 1,812 yards and 13 TDs since taking over for fellow freshman Baker Mayfield, who injured his right knee in the Red Raiders win over Kansas. Webb picked up right where Mayfield left off, and Tech has the second best passing game in the country.

Webb will meet a Cowboys pass defense championed by senior defensive backs Justin Gilbert and Daytawion Lowe. Gilbert is first in the Big-12 with four interceptions, including one returned for a touchdown, and Lowe has two picks of his own.

OSU’s Desmond Roland earned conference player of the week honors for his 219 yards and four touchdowns in last week’s 58-27 blowout over Iowa State. The performance moved the junior into second in the Big-12 with six rushing scores.

He’ll face a Tech rushing defense that’s fourth in the conference allowing 3.7 yards per carry. Senior linebacker Will Smith is first on the team with 56 total tackles and 4.0 sacks, and senior d-lineman Kerry Hyder has recorded 10 tackles for a loss of 32 yards.

Both could also create trouble for Cowboys quarterback J.W. Walsh. The sophomore’s thrown for 1,324 yards and nine touchdowns to five picks. His main targets include Josh Stewart (34 catches, 483 yards, 2 TDs) and Tracy Moore (26 catches, 332 yards, 1 TD).

The Red Raiders have lost four straight to OSU, and five of the last six dating back to 2007. But Tech owns the all-time mark at 21-16-3.

Point Spread: Oklahoma State is favored by 1 point

Over/Under: 69 points

Kickoff Time: 7 p.m. Eastern Time

TV Channel: FOX

Prediction: Oklahoma State 38, Texas Tech 34

National Football League