The top after-market NASDAQ stock market losers are: SurModics, Cisco Systems, Ascent Solar Technologies, Cavium Networks, Micromet, Stereotaxis, Kulicke & Soffa Industries, Optimer Pharmaceuticals, Altera, and NetLogic Microsystems.

SurModics Inc. (SRDX) lost 21.89 percent to $10.24 in the after-market trading. The company's fourth quarter loss was $21.7 million or $1.25 a share, compared to profit of $2.7 million or 16 cents a share last year. Adjusted loss was $0.9 million or 13 cents a share. Revenue declined to $15.5 million from $19.2 million. Analysts had expected profit of 13 cents a share on revenue of $19.3 million.

SurModics expects fiscal 2011 adjusted results between loss 15 cents and profit 5 cents a share, and revenue of $55 million to $63 million. Analysts expect profit of 63 cents a share on revenue of $82.7 million.

Cisco Systems, Inc. (CSCO) plunged 12.62 percent to $21.40 in the after-hours session. The company's first quarter adjusted profit was $2.4 million or 42 cents a share, up from $2.1 million or 36 cents a share last year. Sales rose 19 percent to $10.7 billion. Analysts had expected profit of 40 cents a share on revenue of $10.74 billion.

Chief executive John Chamber said in a conference call that Cisco expects second quarter sales to grow 3 percent to 5 percent year-over-year, implying sales of $10.11 billion to $10.31 billion, lower than analysts forecast of $11.08 billion.

Cisco expects fiscal 2011 sales to grow 9 percent to 12 percent, implying sales of $43.64 billion to $44.84 billion, lower than analysts guidance of $45.28 billion.

Ascent Solar Technologies, Inc. (ASTI) plummeted 10.09 percent to $4.10 in the after-market trading. The company said it plans to begin an underwritten public offering of its common stock. Net proceeds are expected to be used for the completion of the company's 30 megawatt FAB2 production plant and for general corporate purposes.

Cavium Networks, Inc. (CAVM) fell 6.39 percent to $32.37 in the after-hours session.

Micromet, Inc. (MITI) dropped 6.25 percent to $7.50 in the after-market session. The company said it plans to sell shares of its common stock pursuant to an underwriting agreement with Piper Jaffray & Co. Closing of the offering is expected to occur on or about Nov. 16.

Micromet intends to use the net proceeds from the financing primarily for general corporate purposes, which may include research and development, capital expenditures, working capital and general and administrative expenses.

Stereotaxis Inc. (STXS) tumbled 6.25 percent to $3.75 in the after-hours trading. The company plans to offer its common stock in a registered public offering pursuant to its existing shelf registration statement under the Securities Act of 1933.

Separately, Stereotaxis said it has received a commitment letter from Silicon Valley Bank for an amended credit agreement that extends its revolving $30 million credit facility to March 31, 2012. The company agreed with these shareholders to extend guarantee through March 31, 2012 in exchange for warrants to buy its 800,000 common shares.

Kulicke & Soffa Industries Inc. (KLIC) declined 6.12 percent to $5.98 in the after-market session. The company's fourth quarter earnings from continuing operations were $56.1 million or 78 cents a share, up from $5.8 million or 8 cents a share last year. Revenue rose 134.6 percent to $259.3 million. Analysts had expected profit of 82 cents a share on revenue of $260 million.

Kulicke & Soffa expects first quarter revenue of $125 million to $135 million, while analysts forecast $214.58 million.

Optimer Pharmaceuticals, Inc. (OPTR) decreased 5.77 percent to $8.99 in the after-hours trading. The company said in a regulatory filing that it has informed FDA on the voluntarily termination on the research study on its investigational prodrug, Pruvel or Prulifloxacin.

Optimer said the termination was due to a higher than expected incidence of cutaneous rash during the course of study of the possible interaction between Pruvel and antacids. Pruvel, which is in the fluoroquinolone class of antibiotics, was being developed as a treatment for infectious diarrhea, including travelers' diarrhea, that can be caused by a broad range of bacteria.

Altera Corp. (ALTR) fell 5.41 percent to $32 in the after-market trading.

NetLogic Microsystems Inc. (NETL) moved down 5.10 percent to $29.76 in the after-hours session.

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