The top after-market NASDAQ gainers Thursday were NuPathe Inc, Education Management Corporation, Life Technologies Corporation and Unilife Corporation, while the top after-market NASDAQ losers were Trius Therapeutic Inc, Intel Corporation, MAKO Surgical Corp, J.B. Hunt Transport Services Inc and Oncothyreo Inc.

Gainers

NuPathe Inc (NASDAQ: PATH) shares climbed 14.93 percent to $3.96 in post-market trading. The company announced that the U.S. Food and Drug Administration (FDA) have approved Zecuity™ for the acute treatment of migraine with or without aura in adults. The stock has a 52-week low of $1.87, a 52-week high of $5.10 and $48.84 million in market capitalization.

Education Management Corporation (NASDAQ: EDMC) shares gained 8.47 percent to $4.10 in post-market trading. The stock has a 52-week low of $2.84, a 52-week high of $26.70 and $470.61 million in market capitalization.

Life Technologies Corporation (NASDAQ: LIFE) shares advanced 8.24 percent to $59.50 in post-market trading. The stock has a 52-week low of $39.73, a 52-week high of $55.10 and $9.46 billion in market capitalization.

Unilife Corporation (NASDAQ: UNIS) shares rose 4.67 percent to $2.69 in post-market trading. The stock has a 52-week low of $2.01, a 52-week high of $5.17 and $199.61 million in market capitalization.

Losers

Trius Therapeutic Inc (NASDAQ: TSRX) shares declined 5.35 percent to $4.95 in post-market trading. The stock has a 52-week low of $4.41, a 52-week high of $6.49 and $206.09 million in market capitalization.

Intel Corporation (NASDAQ:INTC) shares slumped 5.29 percent to $21.48 in post-market trading. The stock has a 52-week low of $19.23, a 52-week high of $29.27 and $112.86 billion in market capitalization.

MAKO Surgical Corp (NASDAQ: MAKO) shares dropped 2.74 percent to $11.01 in post-market trading. The stock has a 52-week low of $10.35, a 52-week high of $45.15 and $486.1 million in market capitalization.

J.B. Hunt Transport Services Inc (NASDAQ:JBHT) shares fell 2.29 percent to $61.34 in post-market trading. The stock has a 52-week low of $47.81, a 52-week high of $63.22 and $7.42 billion in market capitalization.

Oncothyreo Inc (NASDAQ: ONTY) shares declined 2.22 percent to $2.20 in post-market trading. The stock has a 52-week low of $1.71, a 52-week high of $9.23 and $128.68 million in market capitalization.