The top after-market NYSE gainers Wednesday were ServiceNow, Las Vegas Sands Corp, Owens-Illinois, Fair Isaac Corp and MGIC Investment. The top after-market NYSE losers were Fusion-io, ResMed, Vanguard Natural Resources, Medifast and YPF SA.

Gainers

ServiceNow Inc. (NYSE:NOW) shares rallied 8.01 percent to $31.29 in post-market trading. Its fourth quarter adjusted net loss narrowed to $0.6 million or $0.00 per share from $3.6 million or $0.17 per share in the same quarter last year. Quarterly revenues surged 92 percent to $75.16 million from $39.18 million last year. The company currently expects the first quarter revenues to be in a range of $81.5 to $82.5 million, above the analysts’ estimate of $78.09 million.

Las Vegas Sands Corp. (NYSE:LVS) shares surged 5.22 percent to $54.25 in post-market trading. The company reported the fourth quarter net income of $435 million or $0.53 per share, up from $320 million or $0.39 per share in the same period last year. Quarterly revenue surged to $3.08 billion from $2.54 billion last year and also topped Reuters’ estimate of $3.01 billion.

Owens-Illinois Inc. (NYSE:OI) shares surged 4.31 percent to $23.74 in post-market trading. Its fourth quarter adjusted net profit declined to $0.40 per share from $0.48 per share in the same period last year but topped the analysts’ estimate of $0.37 per share.

Fair Isaac Corp. (NYSE:FICO) shares gained 3.29 percent to $45.90 in post-market trading. The company raised its fiscal 2013 earnings guidance to a range of $760 to $770 million from its prior estimate of $740 to $750 million and above the analysts’ estimate of $744.52 million.

MGIC Investment Corp. (NYSE:MTG) shares advanced 2.71 percent to $2.65 in post-market trading. The stock has a 52-week low of $0.66, a 52-week high of $5.15 and $521.24 million in market capitalization.

Losers

Fusion-io, Inc. (NYSE:FIO) shares tumbled 17.37 percent to $16.60 in post-market trading. The company expects the first quarter revenue to be approximately $80 million and fiscal 2013 revenue to be in a range of $420 to $440 million, widely missing the analysts’ estimate of $137.20 million for the first quarter and $530.06 million for the full year.

ResMed Inc. (NYSE:RMD) shares slumped 5.96 percent to $44.05 in post-market trading. The stock has a 52-week low of $28.67, a 52-week high of $48.47 and $6.70 billion in market capitalization.

Vanguard Natural Resources LLC (NYSE:VNR) shares plunged 4.60 percent to $27.80 in post-market trading. Vanguard Natural announced Wednesday that it had commenced a public offering of 8,000,000 common units representing limited liability company interests in the company, pursuant to an effective shelf registration statement on Form S-3 filed with the Securities and Exchange Commission on January 18, 2012.

Medifast, Inc. (NYSE:MED) shares declined 4.05 percent to $22.77 in post-market trading after plunging more than 8 percent in regular trading.

YPF SA (NYSE:YPF) shares fell 3.86 percent to $16.70 in post-market trading. The stock has a 52-week low of $9.21, a 52-week high of $36.70 and $6.83 billion in market capitalization.

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