NFL Week 7 Picks Against The Spread 2021: Predictions ATS, Betting Odds, Matchups

All 13 games on the NFL Week 7 schedule feature a betting line of at least three points. It’s the first time in the 2021 season that a pair of teams are favored by more than 15 points on the same day. There are four home underdogs.

Here are picks against the spread for every game in Week 7, as well as updated betting odds. Betting lines come from FanDuel Sportsbook.

Denver Broncos (+3) at Cleveland Browns

All of their injuries make the Browns prime candidates to be upset Thursday night. Even if Baker Mayfield plays, his shoulder injury could limit his effectiveness. Cleveland’s two star running backs and both starting tackles were hurt Sunday. Denver has an elite run defense. If Teddy Bridgewater can avoid making too many costly mistakes, the Broncos can win outright.

Prediction ATS: Denver

Cincinnati Bengals (+6) at Baltimore Ravens

Baltimore’s slim one-game lead over Cincinnati doesn’t accurately reflect the gap between the AFC North rivals. The Bengals haven’t beaten a team with a winning record. Before defeating the winless Lions, Cincinnati hadn’t scored more than 24 points in regulation. Lamar Jackson is playing as well as any quarterback. The Ravens’ defense has held their last four opponents to 13.8 points per game.

Prediction ATS: Baltimore

Carolina Panthers (-3) at New York Giants

During Carolina’s three-game losing streak, Sam Darnold has thrown four touchdown passes, six interceptions and completed just 54.7% of his passes. Christian McCaffrey will miss several more games. The Giants should have the better offense if some of their weapons return from injury.

Prediction ATS: New York

Washington Football Team (+9.5) at Green Bay Packers

Washington hasn’t been very competitive against the best teams on its schedule, while Green Bay is taking care of business against teams it's supposed to beat. Taylor Heinicke is 0-3 against playoff teams with three losses by double digits. During their five-game winning streak, the Packers have won both home games by double digits. Since getting blown out in the season opener, Green Bay has had a top-five defense.

Prediction ATS: Green Bay

Kansas City Chiefs (-5.5) at Tennessee Titans

For the last year, the Chiefs have made it a habit of failing to cover the spread in wins against good teams. Derrick Henry should pile up a ton of yards against a Kansas City defense that surrenders 5.2 yards per carry. The Titans are eighth in points scored. The Chiefs have given up at least 29 points in all four of their matchups with top-12 scoring offenses.

Prediction ATS: Tennessee

Atlanta Falcons (-2.5) at Miami Dolphins

The Falcons have an extra week to prepare for the Dolphins, coming off a bye after their victory in London. Miami is back in action seven days after losing in London to Jacksonville, who snapped its 20-game losing streak. Atlanta is 2-0 against one-win teams. Miami hasn’t won since the season opener.

Prediction ATS: Atlanta

New York Jets (+7) at New England Patriots

Five weeks ago, the Jets lost at home to the Patriots 25-6. Things won’t be much different on the road. New York has an 11-game losing streak against New England. Since Tom Brady left the Patriots, the Jets have still lost to their AFC East rivals by an average score of 27-16. Mac Jones’s passer rating is 26.7 points higher than that of Zach Wilson.

Prediction ATS: New England

Detroit Lions (+15.5) at Los Angeles Rams

It’s hard to lay nearly 16 points against a Detroit team that has been competitive against multiple playoff contenders. Before getting blown out by the Bengals, four of the Lions’ five losses came by 10 points or fewer. In Week 15 of last season, the Rams lost outright as 17-point home favorites against the Jets. Detroit is desperate to pick up its first win of 2021.

Prediction ATS: Detroit

Philadelphia Eagles (+3) at Las Vegas Raiders

This is a game the Raiders should win if they are serious about making the playoffs. Las Vegas has a top-10 offense and the league’s fewest turnovers. Against teams with winning records, the Eagles are 0-3 and have been outscored 111-73.

Prediction ATS: Las Vegas

Chicago Bears (+13.5) at Tampa Bay Buccaneers

Given their injuries in the secondary, Tampa Bay shouldn’t be laying two touchdowns against a .500 team. Justin Fields should have his best game as a pro. Chicago beat Tampa Bay straight up a year ago. Expect a game similar to Week 6, when the Bucs let the Eagles hang around and beat Philadelphia, 28-22.

Prediction ATS: Chicago

Houston Texans (+17) at Arizona Cardinals

Maybe Arizona will overlook Houston and the Texans can avoid being blown out for the first three quarters. Both of the Cardinals’ wins over sub.-.500 teams have come by fewer than 13 points. This is a difficult game to bet, either way.

Prediction ATS: Houston

Indianapolis Colts (+3.5) at San Francisco 49ers

Why is San Francisco favored by more than a field goal? Both teams have two wins, and Indianapolis has only lost to playoff teams. The Colts are a fourth-quarter meltdown away from being on a three-game winning streak. Neither Jimmy Garoppolo nor Trey Lance has been better than Carson Wentz.

Prediction ATS: Indianapolis

New Orleans Saints (-5.5) at Seattle Seahawks

This is a bad matchup for Seattle with Geno Smith at quarterback. The Saints allow the fewest yards per carry in the NFL. Jameis Winston is prone to turning the ball over, but the Seahawks only have two interceptions. Seattle hasn’t had a home-field advantage, losing both games at Lumen Field.

Prediction ATS: New Orleans

Season Record: 43-49-2