What Is Jerry Lewis' Cause Of Death? Comedy Legend Dies At 91

Entertainment icon Jerry Lewis has died of natural causes Sunday morning at his home in Las Vegas. He was 91.

The comedian and filmmaker’s death, first reported by the Las Vegas Journal Review Sunday, received confirmation from his family members. He died at about 12:15 a.m. ET.

"Famed comedian, actor and legendary entertainer Jerry Lewis passed away peacefully today of natural causes at 91 at his home in Las Vegas with his family by his side," his family told the Review-Journal.

Lewis, born Joseph Levitch, had reportedly been hospitalized from June 10 to Aug. 7 for a urinary tract infection.

Although the proclaimed king of entertainment remained active, he faced different health-related issues in his later years — he suffered two heart attacks, prostate cancer, pulmonary fibrosis, a chronic lung disease and Type 1 diabetes.

The drugs doctors prescribed him caused issues like weight gain, though he would endure and continue to perform. He performed one-man shows in front of sold-out crowds at the La Mirada Theatre for the Performing Arts in California in 2014.

Lewis spent most this summer hospitalized. His spokesperson confirmed that he had a urinary tract infection and received medical treatment for precautionary measures due to his age, NBC-affiliate KSNV reported June 9.

On June 5, his spokesman had said that he was progressing and the medication was effective. Though doctors expected his stay to be short, Lewis remained hospitalized.

Lewis has had a long history of medical problems. The military barred him from participation in World War II because of a heart murmur. He had endured spinal cord surgery in the 1970s and had open-heart surgery in the 1980s.

Despite health issues, the famed entertainer remained active in films. Lewis appeared in the 2013 Brazilian film, "Till Luck Do Us Part 2" and appeared in a 2016 film "The Trust," alongside Nicolas Cage and Elijah Wood.

Lewis was born in Newark, New Jersey, on March 16, 1926. He started performing at 5 years old alongside his parents in the Catskill Mountains.

He gained notoriety in 1946 alongside Dean Martin where they acted in television, radio shows and movies together before their partnership ended in 1956. "Martin and Lewis" became one of the great comedy duos of all-time. He also received famed for "The Jerry Lewis MDA Labor Day Telethon," an annual TV event to raise money for the Muscular Dystrophy Association (MDA).

Lewis starred in, produced and directed many films including "The Delicate Delinquent" in 1957, "The Bellboy" in 1960 and "The Nutty Professor" in 1963.

Lewis never received an Oscar nomination, though he did get a Golden Globe nomination in 1966 for the film "Boeing, Boeing."

Lewis is survived by his children, sons Gary, Ronnie, Scott, Christopher and Anthony and daughter Danielle. His youngest, Joseph, 45, died Oct. 29, 2009, from a drug overdose

He married twice, his first wife Patti Palmer, from 1944 to 1980, then to SanDee Pitnick, from 1983 until his death.

Touched by Lewis’ legacy, celebrities like Jamie Lee Curtis, William Shatner and Russell Simmons took to social media to extend their appreciation.