Khloé Kardashian
Khloé Kardashian, photographed at Cosmopolitan magazine's 50th birthday celebration in West Hollywood, California, on Oct. 12, 2015, is reportedly hoping that her estranged husband, Lamar Odom, will make some serious changes in his lifestyle following his hospitalization. Getty Images

Lamar Odom's recent hospitalization took a major toll on the Kardashian family, especially his estranged wife, Khloé Kardashian. The former NBA star regained consciousness Oct. 16 after four days in a coma and those closest to him are hopeful they can put this, and any worries that he will continue using drugs, behind them.

Sources close to the Kardashian family, who rose to fame on E!'s his series "Keeping Up With the Kardashians," tell People magazine Khloé, 30, was afraid something like this would happen to Odom, 35. She, along with the rest of the ex-Los Angeles Lakers player's family and friends, is crossing her fingers it will serve as a catalyst for change, inspiring her estranged hubby to clean up his act. The publication reports that those close to Odom want him to live up to his full potential and know he cannot do that without making some serious changes to his lifestyle.

"This is exactly what she feared," the source said. "Everyone is hoping that this will be a reality check for him and that he will make a change in his life and be the man he was created to be."

Khloé opened up about Odom's hospitalization for the first time Tuesday. In a statement, released on her website, the "KUWTK" star thanked family, friends and fans for their kind words during this challenging time. She also took a second to give thanks to the staff at Sunrise Hospital, whom she called "amazing," for their "diligent work" and being so kind and reassuring to those sitting at Odom's bedside. She ended her message by simply saying, "God is great!!!"

As International Business Times previously reported, Odom is on the road to recovery, but is not out of the woods just yet. It has since been revealed that, after opening his eyes less than a week ago, the once promising basketball player has been able to communicate verbally and move from his bed with assistance. A majority of his once-failing vital organs are also said to be on the mend. His kidneys, however, reportedly continue to fail. He is said to be getting six hours of dialysis daily, though doctors are considering new avenues to do away with that treatment. The staff at Cedars-Sinai medical center in Los Angeles, where he was moved Monday, are said to be looking into getting him on a transplant list.