Champions Manchester United faces the tough trip to Stoke City on Saturday; a match many reckon will end United's perfect start to the season.
Arsenal host Bolton Wanderers at the Emirates on Saturday, and both sides will hope to secure a vital three points and some much-needed confidence.
The Blues may look to bolster their squad with some late-season additions
After coming out with many positives despite a 3-1 defeat at Manchester United, Chelsea will face neighbors Fulham in the Carling Cup third round on Wednesday.
A weakened Manchester United proved too much for bitter-rivals Leeds United while Arsenal came back from a goal down to beat league two side Shrewsbury 3-1.
A weakened Manchester United proved too much for bitter-rivals Leeds United as the visitors secured a 3-0 victory at Elland Road in the Carling Cup third round.
The Carling Cup third round offers a special treat for the football connoisseur as Manchester United travel to Elland Road to face old-rivals Leeds United.
We present the chosen three best goals of the week here and readers can decide which one they think is the best.
Manchester City succumbed to a 2-2 draw at Craven Cottage despite having a two-goal advantage over Fulham.
An eventful game ended with Manchester United securing a 3-1 win over Chelsea at Old Trafford, although the match will be remembered more for the number of missed chances than the well-taken goals.
The Red Devils defeated the Blues, 3-1
The Red Devils get three first half goals to beat the Blues.
Andre Villas-Boas will face his toughest challenge as Chelsea manager to-date when his side travels to Old Trafford to take on the champions Manchester United on Sunday.
Andre Villas-Boas will face his toughest challenge as Chelsea manager to-date when his side travels to Old Trafford to take on the champions Manchester United on Sunday.
Andre Villas-Boas' will face his toughest challenge as Chelsea manager to-date when his side travels to Old Trafford to take on the champions Manchester United on Sunday.
Two top Premier League clubs meet at Old Trafford.
United host the Blues at Old Trafford.
Arsenal's revival was put to an end by bottom-of-the-table Blackburn Rovers after the home team secured a 4-3 win at Ewood Park.
The Red Devils face the Blues at Old Trafford.
Arsenal's revival was put to an end by bottom-of-the-table Blackburn Rovers after the home team secured a 4-3 win at Ewood Park.
Arsenal will travel north to Blackburn for Saturday's early kick-off, in a bid to continue their recent revival after a torrid start to the season.
Get briefed on the weekend's action as Manchester United and Chelsea face each other in an early-season grand slam while Liverpool and Tottenham will also battle it out at White Hart Lane.