The Seahawks will face their biggest test of the season on Sunday night, at home against the Chiefs.
The Pittsburgh Steelers are likely to win the AFC North over the Baltimore Ravens.
The Seahawks will likely still make the playoffs, but clinching a berth this week could prove tricky.
The Browns and Panthers are still in playoff contention, despite having losing records.
The Dallas Cowboys are headed for the No.4 seed in the playoffs.
The Chiefs could miss multiple starters against the Seahawks on Sunday night.
The New England Patriots will be thin at the skill positions after wide receiver Josh Gordon announced he will step away from football.
Tom Brady is speculated to be playing through an MCL injury.
Entering Week 16, the New Orleans Saints and Los Angeles Rams are the top favorites to win Super Bowl LIII in Atlanta.
The 24-year-old quarterback had most recently played for the Buffalo Bills.
Cam Newton probably won't play again in 2018 and the Carolina Panthers will almost certainly miss the playoffs.
The Baltimore Ravens will make the playoffs if they win their next two games.
The Green Bay Packers will spend January at home, but Aaron Rodgers might still play the last two games of the season.
The Indianapolis Colts have been resurgent in the second half of the season, but their margin for error to make the playoffs is still slim.
The Washington Redskins will be hard-pressed to make the playoffs.
Cowboys owner Jerry Jones said former first-round pick Taco Charlton needs to get more playing time.
Here are betting lines for all of the games on the NFL Week 16 schedule.
The Steelers and Titans have the best odds to secure the final AFC playoff berths.
The New Orleans Saints are a win away from securing home-field advantage in the NFC playoffs.
Patrick Mahomes has taken over at the front from Drew Brees in the race for the NFL regular season MVP.
Rob Gronkowski is "a shell of himself" according to former New England Patriots player Damien Woody.
The Chiefs and Seahawks will meet in Seattle for a huge, late-season matchup between AFC and NFC powers.